FPI prediction: MIN, 71.6% (by an average of 7.9 points), Matchup must-reads: Jones brings new energy, hope to Giants What's happened to Thielen and Diggs? FPI prediction: SF, 72.5% (by an average of 8.3 points), Matchup must-reads: Chubb's running finally launches Browns' offense How good are first-place 49ers? What's more, it's Mayfield at quarterback for the Panthers this time, the same signal-caller Bosa made a point of terrorizing in 2019 with two sacks, a forced fumble and a fumble recovery. His 43.1 QBR this season is also his worst through the first four games in that same time frame. FPI prediction: CIN, 56.2% (by an average of 2.2 points), Matchup must-reads: Cardinals WR Kirk likely out Sunday but ankle better Bengals put WR Ross on IR with shoulder injury, 4:05 p.m. Even at full strength, Seattle's offensive line will have its hands full against a Rams front four that has given the Seahawks all sorts of trouble during the past few seasons. -- Tim McManus. DET-NE | CHI-MIN | MIA-NYJ Stat to know: The Vikings have allowed at least 300 yards in 12 straight games dating back to last season. Read more. Jump to a matchup: There have been 45 Longhorns selected in the first round. NFL best bets and picks for Week 5: Take the 49ers and the points, and the Jets-Falcons over. Stat to know: The Niners' Jeff Wilson Jr. has scored multiple rushing touchdowns in two straight games. -- Mike DiRocco. But since 2017, his 29% completion rate ranks 38th out of 43 passers with at least 50 such attempts. While the Chargers' running game has struggled, Herbert will always be a threat in the passing game. -- John Keim, Bold prediction: Titans quarterback Ryan Tannehill will finish with 300 passing yards in a win over the Commanders. 2023 NFL mock draft: Todd McShay's final first-round predictions - ESPN Victor Cruz contends that Gardner Minshew is better equipped to lead his team to victory in the matchup with Panthers QB Kyle Allen. FPI prediction: CAR, 57.9% (by an average of 2.8 points), Matchup must-reads: Fournette flourishes in Christian McCaffrey-type workload Amid defensive changes, Kuechly remains the Panthers' stopper Jaguars looking to cash in on Minshew mania Khan: No plan to trade CB Jalen Ramsey, 1 p.m. 3 all-time rusher Barry Sanders, Meet Brady's most trusted teammate: His 1995 shoulder pads, Redskins' January decision to maintain status quo looks bad in hindsight, Patriots' offense searching for identity, as it did in 2018, Big pass plays tearing up Ravens' defense, 'Do whatever' to win: Steelers bring back the Wildcat, Raiders hoping to reverse London trend by changing travel schedule, Left with no defense, Jackson needs to carry Ravens this season, Steelers' first draft by Khan 'aggressive', Mack expected to be with the Raiders 'for the long haul', Daniel embraces seldom-used, uncertain backup QB life, Carr: Burfict's 'heart is broken;' QB says ban isn't fair, Analyzing how, where Golden Tate fits into Giants' offense. For context, 5.2 yards per rush with McCoy on the field would rank fifth in the NFL among all teams this season, as opposed to 27th when McCoy isn't on the field. Read more. They have the NFL's second-ranked rushing defense, surrendering only 59.3 yards per game, and they held Christian McCaffrey to just 37 rushing yards in Week 2 (53 all-purpose yards) and the Rams to just 28 total rushing yards in Week 4. Read more. -- Josh Weinfuss. Week 5 NFL game picks: Chiefs top Bills; Cardinals stay perfect with win over 49ers. NE-WSH | BAL-PIT | OAK-CHI Stat to know: Tampa Bay's Shaquil Barrett leads the NFL with 9.0 sacks through four games. It helps the Chargers are also winless (0-4) and can't run the ball (28th in NFL). NFL: Notable Super Bowl betting trends -- Marcel Louis-Jacques. That would mean bigger roles for undrafted rookie Keelan Cole (four catches) and recently signed first-year player Max McCaffrey. NFL draft 2023: Biggest post-draft questions for all 32 teams - ESPN -- Jeff Dickerson, Biggest post-draft questions What to know for fantasy: DK Metcalf had the big Week 4, but Tyler Lockett has benefited most from the overachieving of Smith more than 75 receiving yards in three straight games. ET games. Thus, breaking the streak won't be easy for the Ravens. See Week 5 rankings. ET | CBS The NFL reporter use his Twitter account to share insight about the league's upcoming 2023 schedule . -- Kevin Seifert, Bold prediction: Kirk Cousins will have another three-interception day against the Bears' defense, akin to the last time the Vikings played against Matt Eberflus in Indianapolis, where Cousins recorded a 15.7 passer rating and three picks. Full list of Mr. Irrelevants in NFL draft history: Is Brock Purdy already the best final pick? 1 in both defensive efficiency and QBR allowed in that span. -- Todd Archer, Bold prediction: The first team to 30 rushing attempts will win. Injuries: Eagles | Steelers. Here are some lines that could change after this week's slate concludes. -- Rob Demovsky. Around The NFL Podcast Co-Host. Week 5 NFL game picks: Chiefs top Bills; Cardinals stay perfect with Packers vs Bengals Odds, Picks and Predictions - Tiger Balm - Covers.com Time/station: 8:20 PM EST, ESPN. That should change against a Tampa Bay team that is averaging 31 points per game and allowing 29. -- Courtney Cronin. The story of the Cowboys scout and prospect son Dallas just drafted, Legacy pick: Cardinals take great-great-nephew of team's first-ever draft pick, Winston already improving under 'QB whisperer' Bruce Arians, Yes, he's 2-0, but the Saints will need more from Bridgewater, Matthew Berry's Love/Hate for Week 5: How to make a trade, NFL experts predict: Week 5 upset picks, fantasy football flops and sleepers, How Watson's 'NFL experience' began as ball boy for the Falcons, TE Hooper could be the next Falcon to cash in, Taylor Lewan's return could be a boon for Titans' offense, Gore closing on No. The Vikings are banged up on offense but probably still good enough to squeak out a close victory. What to know for fantasy: Jameis Winston has thrown three-plus touchdown passes in consecutive games for the first time in his career, but now he gets a Saints team against which he has never thrown three-plus touchdown passes in a game. But the key in this one will be the ability of the Carolina defense to make the Lions one-dimensional and force Matthew Stafford to beat them. Atlanta has rushed for at least 179 yards in three of its four games. Betting nugget: Philadelphia is 3-0 ATS against Pittsburgh since 2008. -- Jamison Hensley, Bold prediction: Ja'Marr Chase will have more than 125 receiving yards. -- Tim McManus. Stat to know: Rodgers is averaging 6.2 air yards per attempt, his fewest through four games since becoming a starter in 2008. -- Rich Cimini. What to know for fantasy: Breece Hall has a touchdown or six catches in all four games this season and seems to be trending in the direction of a lineup lock. The answer is to be determined, Cruz expects Minshew will lead Jags over Allen's Panthers (1:17), Week 5 NFL game picks, schedule guide, fantasy football tips and more, Which NFL teams still have roster holes? What to know for fantasy: After scoring 11 times in his first 14 games last season, Hopkins has scored just twice in his past seven games (playoffs included). So, these teams could have to rely on their defenses. Stat to know: The Titans rank 28th in the NFL in both sacks allowed (17) and pressure rate (34.0%). The Chiefs are averaging 5.2 yards per rush this season with McCoy on the field, compared to 3.3 with him off the field. What will help you is the fact that the GOAT is averaging 28.0 PPG as a Buccaneer against the Falcons. Moody's pick: Chargers 27, Browns 20 He had just 14 receptions for 174 yards and zero TDs in 11 games last season. 125 attempts). Chalk home | NFL home | CFB home, Bold prediction: The Cardinals' passing game will finally lead them to a win. ET | Fox FPI prediction: KC, 80.9% (by an average of 12.0 points), Matchup must-reads: Mahomes, Favre and other NFL stars reveal the larger-than-life tales behind Andy Reid Colts GM Chris Ballard has needed his no-flinch, no-panic approach Chiefs RB Williams has waited behind big-name backs before Ebron 'disgusted' by drops, takes blame for Colts' loss, Monday, 8:15 p.m. See Week 5 rankings. Gutierrez's pick: Bears 20, Raiders 16 Watch on ESPN+, Bold prediction: Ravens rookie receiver Marquise Brown gets back on track after two lackluster games with 100 yards receiving and two long touchdown catches. These teams are evenly matched, so quarterback play could make the difference. What to know for fantasy: Barkley has more than 20 carries or a rushing TD in all four games this season and leads the league in percentage of team offense accounted for (40.4%). Read more. That will make it even harder for the Jaguars to do much in the passing game, especially downfield, to open things up for RB Leonard Fournette. The Bills' offense -- which has gone three-and-out on 48 percent of drives this season, second most in the NFL -- will be playing short-handed at wide receiver because of a thumb injury to No. NYG-GB | ATL-TB | PIT-BUF In most cases, he'd be right, but there has been a sense of satisfaction this week in the Jets' locker room -- a possible red flag. Since Alex Smith got injured in Week 11 of last season, it has had an NFL-high five starting QBs. The Commanders have allowed 1.17 yards after contact, also second best the past two weeks. 1 overall pick, are hours away from being on the clock -- which means the 2023 NFL draft has arrived. Dickerson's pick: Bears 19, Raiders 6 The latest hint that the Jets are destined for the spotlight came from ESPN's Adam Schefter. Stat to know: Chargers receiver Keenan Allen leads the NFL with 452 receiving yards, and he is the only player with more than 400. Chuck Pagano has never started a season 1-4 as coach of the Colts. Matchup rating: 44.9 | Spread: CHI -5 (40.5), What to watch for: Khalil Mack will be looking to take over the game against his former teammates. The Packers opened the season with a disastrous loss at New Orleans . Another big day could be in store for Bosa here, and don't be surprised if he brings back the "flag plant" celebration he used against Mayfield in that previous meeting. Their offense is clicking on all cylinders, and their defense finally showed signs of life in the second half Sunday, holding Dallas to a mere six points. It's ranked fourth in rushing yards allowed per play (3.2), while the Eagles are ranked fifth in rushing yards gained per play (4.7). -- Katherine Terrell, Bold prediction: Ryan Neal will take over for Josh Jones in the starting lineup and spark Seattle's struggling defense with a game-changing takeaway. NFL Expert Picks, Predictions, Lines: Week 5 - College Football News NFL Week 5 Early Odds, Picks & Predictions (2022) | BettingPros They'll be energized, while at home against a tough division rival, and will sneak out another close win. Sure, the Packers have found replacements for all three, but those were big-time players who performed in the clutch. 1, Panthers' Bryce Young is all 'business now', Top picks Christian Gonzalez, Keion White reflect Patriots' ideal identity, Big takeaways from the NFL draft: A historic QB class, the rebuilt AFC South and new GMs thriving, NFL Nation sizes up all 259 draft selections, XFL semifinals: Defenders roll Sea Dragons, set up title showdown with Renegades. Get the latest NFL Week 5 picks from CBS Sports. Las Vegas Raiders vs. Kansas City Chiefs picks, predictions NFL Week 5 Stat to know: Trevor Lawrence struggles under pressure, having the largest drop-off of any QB in QBR (-76) compared to when he's not pressured. -- Ben Baby. Stat to know: The Patriots are looking to become the first team since the 1988 Browns and Dolphins to allow zero passing touchdowns in the first five games of the season. The last thing the Vikings need is for Diggs' situation to blow up into a full-blown distraction. The role is great, but don't forget DeAndre Hopkins' suspension has just two weeks left on it. Paired with fellow receivers John Brown and Jaron Brown, the Arizona wideouts pose a threat to a vulnerable Eagles cornerback group. NFL DRAFT HISTORY & NOTES. FPI prediction: PHI, 75.9% (by an average of 9.7 points), Matchup must-reads: Jalen Ramsey to the Eagles: What are the realistic odds? Full list of Mr. Irrelevants in NFL draft history: Is Brock Purdy already the best final pick? Washington's pass defense is allowing 259.8 yards per game, but 294 yards per game at home. He has had 11 passes batted down at the line of scrimmage, six more than any quarterback in the NFL this season. See Week 5 rankings. 2023 NFL draft cheat sheet: Prospect picks, rankings, stats - ESPN Just ask Tampa Bay Buccaneers fans, or Buffalo Bills fans, or Seattle Seahawks fans, or the defense of the Dallas Cowboys.. Betting nugget: Bridgewater is 25-7 against the spread (ATS) in his career as a starting quarterback, the best mark by any QB with at least 15 starts in the Super Bowl era. See Week 5 rankings. NFL: Mahomes favorite for game's MVP 1 min read. Colts 23, 49ers 20 -- Nick Wagoner, The last thing the Colts can do is overlook the 49ers. See Week 5 rankings. But can the Colts keep possession effectively enough to pull the upset? Betting nugget: Over the past 15 seasons, teams favored by at least seven points in international games are 7-0 ATS (6-0 ATS in London). -- Mike DiRocco, Bold prediction: Texans wideout Brandin Cooks will have his best outing of the season with a 100-yard game. Since the start of last season, 13 of the Bills' 20 games have gone under. Gregg Rosenthal went 10-6 . San Francisco 49ers Coach Kyle Shanahan, right, talks with quarterback Trey Lance during a Week 4 loss . Christian McCaffrey, the eighth pick, leads the NFL in rushing with 411 yards, and Jacksonville's Leonard Fournette, the fourth pick, isn't far behind with 404. ET | CBS Given the Colts' struggles protecting the quarterback (they've allowed 14 sacks, tied for fifth most in the league) and the Niners' ability to take advantage of porous offensive lines (nine sacks total against Seattle and Arizona), this would seem to be the type of game the 49ers can win. The Titans' pass defense was a disaster as the Titans gave up 57 points to the Texans in a Week 4 rout. The Bengals are allowing 8.6 yards per attempt, which is ideal for a team averaging 5.5 despite having Kyler Murray -- who has thrown for 300 yards in two of his first four games.
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